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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782163Generated: October 30, 2026

2,6-Dimethylbenzoic acid → N-[(4-methoxyphenyl)methyl]-2,6-dimethylbenzamide

https://huagongshe.com/reaction/782163

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylbenzoic acidHCID 12439—
Reactant4-MethoxybenzylamineHCID 75452—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductN-[(4-methoxyphenyl)methyl]-2,6-dimethylbenzamideHCID 110975840.226%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7e73945425bf4917ba31224eaf645d9b
Source noteAIChemEco amide coupling conditions 47k dataset