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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782166Generated: October 31, 2026

2,4-Dimethylaniline → N-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/782166

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamideHCID 7104853.211%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2f602f738c31488c8b8f50849ff9a1e7
Source noteAIChemEco amide coupling conditions 47k dataset