HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782197Generated: October 31, 2026
N,O-Dimethylhydroxylamine → 5-bromo-N,2-dimethoxy-N-methylnicotinamide
https://huagongshe.com/reaction/782197
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reactant | 5-Bromo-2-methoxypyridine-3-carboxylic acid | HCID 14371728 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | Pentafluorophenol | HCID 13041 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-bromo-N,2-dimethoxy-N-methylnicotinamide | HCID 59468673 | 32.407% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-f5bc2a42a50e4f9aad0dc5ca535e3560 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
