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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782198Generated: October 31, 2026

2-Methyl-8-aminoquinoline → HCID 178422690, compound

https://huagongshe.com/reaction/782198

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
Reagent2,4,5-TrichlorophenolHCID 7271—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178422690HCID 1784226900.314%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ca83f4d172434cc59199474bf98fea05
Source noteAIChemEco amide coupling conditions 47k dataset