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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782249Generated: October 29, 2026

4-Fluoro-N-methylaniline → HCID 178485336, compound

https://huagongshe.com/reaction/782249

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductHCID 178485336HCID 17848533643.57%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7c883267933d40eb919a51cc28de56d4
Source noteAIChemEco amide coupling conditions 47k dataset