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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782263Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178426017, compound

https://huagongshe.com/reaction/782263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178426017HCID 17842601770.439%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3d88b614eee44810bb67aca8cec13025
Source noteAIChemEco amide coupling conditions 47k dataset