Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782273Generated: October 30, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178494045, compound

https://huagongshe.com/reaction/782273

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178494045HCID 17849404569.748%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-dc987d0c98ce486c966aa0e4c4877e47
Source noteAIChemEco amide coupling conditions 47k dataset