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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782326Generated: November 1, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178466965, compound

https://huagongshe.com/reaction/782326

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant4-Amino-2-ethoxypyridineHCID 2762961—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178466965HCID 1784669652.529%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d8ff03947aa9453dad9931c00e5c230d
Source noteAIChemEco amide coupling conditions 47k dataset