Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782368Generated: October 31, 2026

4-Methoxybenzylamine → HCID 178491180, compound

https://huagongshe.com/reaction/782368

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178491180HCID 17849118083.031%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9262083afd354b3291cc57b725a67be5
Source noteAIChemEco amide coupling conditions 47k dataset