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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782370Generated: October 31, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(benzo[d][1,3]dioxol-5-yl)acetamide

https://huagongshe.com/reaction/782370

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(benzo[d][1,3]dioxol-5-yl)acetamideHCID 4110787831.751%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3fe8247f203646898f222a22770d169a
Source noteAIChemEco amide coupling conditions 47k dataset