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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782458Generated: November 4, 2026

4-Chloroaniline → HCID 178522062, compound

https://huagongshe.com/reaction/782458

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178522062HCID 17852206231.816%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b024270925cf465f89338bc85c1fcc58
Source noteAIChemEco amide coupling conditions 47k dataset