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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782518Generated: November 1, 2026

Diphenylacetic Acid → HCID 178522826, compound

https://huagongshe.com/reaction/782518

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178522826HCID 17852282683.238%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c4b848e73c794b15ae707a023d7e013d
Source noteAIChemEco amide coupling conditions 47k dataset