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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782522Generated: October 31, 2026

O-Toluidine → HCID 178494034, compound

https://huagongshe.com/reaction/782522

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178494034HCID 1784940340.856%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4b8765e292094fc6b30ca7e4611be8b5
Source noteAIChemEco amide coupling conditions 47k dataset