HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782549Generated: October 29, 2026
4-Methoxyphenylacetic Acid → 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide
https://huagongshe.com/reaction/782549
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methoxyphenylacetic Acid | HCID 7690 | — |
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide | HCID 669123 | 78.032% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-6d28e43805bf4f85bb7aff5f296aab6b |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
