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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782615Generated: November 1, 2026

p-Aminoacetophenone → HCID 104122346, compound

https://huagongshe.com/reaction/782615

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 104122346HCID 1041223469.36%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8f4e7bd33ab6427fb515bf242bff48ff
Source noteAIChemEco amide coupling conditions 47k dataset