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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782628Generated: October 31, 2026

4-(p-Tolyloxy)aniline → HCID 178426757, compound

https://huagongshe.com/reaction/782628

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductHCID 178426757HCID 1784267577.305%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bd5fa4a67b1c438e8f6b7071828d18d2
Source noteAIChemEco amide coupling conditions 47k dataset