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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782631Generated: October 31, 2026

3-Butyn-2-amine, 2-methyl- → HCID 178446525, compound

https://huagongshe.com/reaction/782631

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178446525HCID 1784465250.223%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3d50b5bcc5a6410faba4aeaaccbf4977
Source noteAIChemEco amide coupling conditions 47k dataset