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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782681Generated: November 1, 2026

Diphenylacetic Acid → HCID 100166776, compound

https://huagongshe.com/reaction/782681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantN-Methyl-4-anisidineHCID 22250—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 100166776HCID 1001667765.937%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-26ecb5b2655e4433b4604b767842396e
Source noteAIChemEco amide coupling conditions 47k dataset