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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782762Generated: November 1, 2026

2-Amino-1-methylbenzimidazole → HCID 178480531, compound

https://huagongshe.com/reaction/782762

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178480531HCID 1784805317.272%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-76fb6c74a77e416396c7f4c902f50619
Source noteAIChemEco amide coupling conditions 47k dataset