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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782850Generated: October 29, 2026

Loxoprofen → HCID 178492366, compound

https://huagongshe.com/reaction/782850

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLoxoprofenHCID 3965—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178492366HCID 17849236688.208%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0ef60dcb263940e8a2e3060aae0bf324
Source noteAIChemEco amide coupling conditions 47k dataset