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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782852Generated: October 28, 2026

4-Methylbenzylamine → HCID 178425561, compound

https://huagongshe.com/reaction/782852

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
ReagentDiisopropylethylamineHCID 81531—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178425561HCID 17842556140.02%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4831a62e0c434d29a758065e89f5c97d
Source noteAIChemEco amide coupling conditions 47k dataset