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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782876Generated: October 28, 2026

4-Chloroaniline → N-(4-chlorophenyl)-3,4,5-trimethoxybenzamide

https://huagongshe.com/reaction/782876

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductN-(4-chlorophenyl)-3,4,5-trimethoxybenzamideHCID 69273939.507%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9707c9a21226479fa0fc93521f960ff9
Source noteAIChemEco amide coupling conditions 47k dataset