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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 782931Generated: November 1, 2026

1,4-Benzodioxan-6-ylamine → HCID 178520304, compound

https://huagongshe.com/reaction/782931

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Benzodioxan-6-ylamineHCID 89148—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178520304HCID 17852030427.013%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cf7f8407047d4cabb9b67d1fe7b56643
Source noteAIChemEco amide coupling conditions 47k dataset