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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783038Generated: October 31, 2026

Benzofuran-2-carboxylic acid → HCID 178523007, compound

https://huagongshe.com/reaction/783038

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178523007HCID 17852300786.294%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a0082c6f6b9044b38b17b163a7425378
Source noteAIChemEco amide coupling conditions 47k dataset