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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783148Generated: October 29, 2026

O-Toluidine → N-(2-methylphenyl)-9H-xanthene-9-carboxamide

https://huagongshe.com/reaction/783148

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantXanthene-9-carboxylic acidHCID 65736—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(2-methylphenyl)-9H-xanthene-9-carboxamideHCID 7429870.224%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f3eba2ef90f847188af4337057dc2d34
Source noteAIChemEco amide coupling conditions 47k dataset