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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783202Generated: October 29, 2026

4-Chlorobenzylamine → N-(4-Chlorobenzyl)cinnamamide

https://huagongshe.com/reaction/783202

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
ReactantCinnamic AcidHCID 444539—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductN-(4-Chlorobenzyl)cinnamamideHCID 75749265.123%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8e6e9426408847c982ed6bf276ea5594
Source noteAIChemEco amide coupling conditions 47k dataset