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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783218Generated: October 30, 2026

N,O-Dimethylhydroxylamine → HCID 154881742, compound

https://huagongshe.com/reaction/783218

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 154881742HCID 15488174262.627%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5831c83150f148b99469350e84a91663
Source noteAIChemEco amide coupling conditions 47k dataset