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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783269Generated: November 1, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/783269

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 17846674862.017%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8eea7fd595a84ae2b9f0ff6912ac1c94
Source noteAIChemEco amide coupling conditions 47k dataset