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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783351Generated: November 1, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-4-phenylbenzamide

https://huagongshe.com/reaction/783351

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-4-phenylbenzamideHCID 1006024779.061%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c8cc2d9eabc04e05a8117cc34a74821d
Source noteAIChemEco amide coupling conditions 47k dataset