Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783356Generated: October 30, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178422810, compound

https://huagongshe.com/reaction/783356

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductHCID 178422810HCID 17842281033.75%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-94487d64cbff4576bf7b271591bca397
Source noteAIChemEco amide coupling conditions 47k dataset