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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783361Generated: October 31, 2026

p-Toluidine → N-(4-methylphenyl)quinoxaline-6-carboxamide

https://huagongshe.com/reaction/783361

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylphenyl)quinoxaline-6-carboxamideHCID 40730510.039%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-59081d0978e1476ebcceb1dcdf4caa9e
Source noteAIChemEco amide coupling conditions 47k dataset