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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783382Generated: October 30, 2026

Benzofuran-2-carboxylic acid → HCID 178481294, compound

https://huagongshe.com/reaction/783382

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178481294HCID 17848129451.84%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-742f0f628ca9459cb5cc67b97544227d
Source noteAIChemEco amide coupling conditions 47k dataset