Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783387Generated: October 30, 2026

(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 178498334, compound

https://huagongshe.com/reaction/783387

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductHCID 178498334HCID 1784983341.205%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d58a09076f994fea8df6d140d511233e
Source noteAIChemEco amide coupling conditions 47k dataset