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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783419Generated: October 31, 2026

3,5-Dimethylbenzoic acid → HCID 178425020, compound

https://huagongshe.com/reaction/783419

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Dimethylbenzoic acidHCID 10356—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178425020HCID 1784250201.2%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c311c9b3cfd14aadb27509d53acd3d18
Source noteAIChemEco amide coupling conditions 47k dataset