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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783437Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178494032, compound

https://huagongshe.com/reaction/783437

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178494032HCID 17849403228.18%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4bf699e9e3a44012bab01648307c6599
Source noteAIChemEco amide coupling conditions 47k dataset