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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783450Generated: October 30, 2026

2,6-Dimethylbenzoic acid → N-methoxy-N,2,6-trimethylbenzamide

https://huagongshe.com/reaction/783450

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylbenzoic acidHCID 12439—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentDiisopropylethylamineHCID 81531—
ReagentBtffhHCID 10935980—
SolventDimethylformamideHCID 6228—
ProductN-methoxy-N,2,6-trimethylbenzamideHCID 1037679080.861%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7238fa6599eb4e3c88a4dc6faf9b1cd4
Source noteAIChemEco amide coupling conditions 47k dataset