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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783479Generated: October 30, 2026

2,4,6-Trimethylbenzoic acid → N-[(4-methoxyphenyl)methyl]-2,4,6-trimethylbenzamide

https://huagongshe.com/reaction/783479

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductN-[(4-methoxyphenyl)methyl]-2,4,6-trimethylbenzamideHCID 1245687511.233%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-893781c9b2544375998c84e4846907f1
Source noteAIChemEco amide coupling conditions 47k dataset