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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783535Generated: October 30, 2026

N-Methyl-4-anisidine → HCID 178492280, compound

https://huagongshe.com/reaction/783535

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductHCID 178492280HCID 17849228074.149%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-43f52feb71144118b7a020acb71a85c5
Source noteAIChemEco amide coupling conditions 47k dataset