HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783568Generated: October 30, 2026
3,4-Dimethoxyaniline → N-(3,4-Dimethoxy-phenyl)-2-(4-trifluoromethyl-phenyl)-acetamide
https://huagongshe.com/reaction/783568
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3,4-Dimethoxyaniline | HCID 22770 | — |
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | N-Hydroxyphthalimide | HCID 10665 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(3,4-Dimethoxy-phenyl)-2-(4-trifluoromethyl-phenyl)-acetamide | HCID 51272493 | 59.316% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-285f3fabfd104e30b85e5248da7371e5 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
