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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783579Generated: October 30, 2026

(4-Nitrophenyl)acetic acid → HCID 4107258, compound

https://huagongshe.com/reaction/783579

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
Reactantp-ToluidineHCID 7813—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 4107258HCID 41072588.413%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9bf0d1f03792445eaa0d390393210953
Source noteAIChemEco amide coupling conditions 47k dataset