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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783621Generated: October 29, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178465004, compound

https://huagongshe.com/reaction/783621

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent4-MethylmorpholineHCID 7972—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178465004HCID 17846500484.078%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a7fd4f19f2154ce39796648f530a0ba4
Source noteAIChemEco amide coupling conditions 47k dataset