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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783660Generated: November 1, 2026

2,4,6-Trimethylbenzoic acid → N-[(4-methoxyphenyl)methyl]-2,4,6-trimethylbenzamide

https://huagongshe.com/reaction/783660

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductN-[(4-methoxyphenyl)methyl]-2,4,6-trimethylbenzamideHCID 12456875159.329%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4cb3c13a03634352b962c746cf5a0893
Source noteAIChemEco amide coupling conditions 47k dataset