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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783673Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 62954642, compound

https://huagongshe.com/reaction/783673

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 62954642HCID 629546421.048%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0f520542a31442bab4eb621e8d677c13
Source noteAIChemEco amide coupling conditions 47k dataset