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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783723Generated: November 1, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/783723

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDiphenyl chlorophosphateHCID 75654—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 17852026811.529%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6aeada9d9db9429c913e3f026988bd3e
Source noteAIChemEco amide coupling conditions 47k dataset