HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-N-methylbenzamide → 4-chloro-3-(trifluoromethyl)phenyl-N'-(4-(3-methylcarbamoylphenyl)carbamoylphenyl) urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-N-methylbenzamide | HCID 676526 | — |
| Reactant | 4-Chloro-3-(trifluoromethyl)phenyl-N'-(4-carboxyphenyl)urea | HCID 23614596 | — |
| Product | 4-chloro-3-(trifluoromethyl)phenyl-N'-(4-(3-methylcarbamoylphenyl)carbamoylphenyl) urea | HCID 23614591 | — |
Reaction Steps
Entry 67: N-(4-Chloro-3-(trifluoromethyl)phenyl-N′-(4-ethoxycarbonylphenyl)urea was synthesized according to Method C1e. N-(4-Chloro-3-(trifluoromethyl)phenyl-N′-(4-ethoxycarbonylphenyl)urea was saponified according to Method D3 to give N-(4-chloro-3-(trifluoromethyl)phenyl-N′-(4-carboxyphenyl)urea. N-(4-Chloro-3-(trifluoromethyl)phenyl-N′-(4-carboxyphenyl)urea was coupled with 3-methylcarbamoylaniline according to Method D1b to give N-(4-chloro-3-(trifluoromethyl)phenyl-N′-(4-(3-methylcarbamoylphenyl)carbamoylphenyl)urea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08841330B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-1008dcdb63024b7c9984d63fc86e0e51 |
| Source note | uspto-grants-2014_09 |