HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dodecanoyl chloride → Dodecanoic acid, 2-(dimethylamino)-1-methylethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dodecanoyl chloride | HCID 8166 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Dimepranol | HCID 37511 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | Dodecanoic acid, 2-(dimethylamino)-1-methylethyl ester | HCID 157516 | — |
Reaction Steps
The (N,N-disubstituted amino)-alkanol alkanoates are readily prepared by reacting the corresponding aminoalkinol with lauroyl chloride in the presence of triethylamine. A solvent such as chloroform is optional but preferred. For example, 1-(N,N-dimethylamino)-2-propanol can be reacted with lauroyl chloride in chloroform and in the presence of triethylamine to form 1-(N,N-dimethylamino)-2-propanol dodecanoate (DAIPD).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08841345B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-bf52ec518a5245d2b9e2bd2b666bbaa9 |
| Source note | uspto-grants-2014_09 |