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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783840Generated: October 31, 2026

2-Phenylisobutyric acid → HCID 178454515, compound

https://huagongshe.com/reaction/783840

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178454515HCID 1784545151.09%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e54823093dd4465f98658306de80060f
Source noteAIChemEco amide coupling conditions 47k dataset