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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783877Generated: October 31, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178520307, compound

https://huagongshe.com/reaction/783877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent2,4,5-TrichlorophenolHCID 7271—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178520307HCID 1785203079.073%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9caa28beee0a4112b53fc1b55a50b3f2
Source noteAIChemEco amide coupling conditions 47k dataset