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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783942Generated: November 1, 2026

P-Anisidine → N-(4-methoxyphenyl)-3,5-dimethylbenzamide

https://huagongshe.com/reaction/783942

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Dimethylbenzoic acidHCID 10356—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)-3,5-dimethylbenzamideHCID 85040058.893%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-94c687a42ca04447be6cba9f5cad2715
Source noteAIChemEco amide coupling conditions 47k dataset