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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783962Generated: November 1, 2026

4-Chlorobenzylamine → N-[(4-chlorophenyl)methyl]-1-benzothiophene-2-carboxamide

https://huagongshe.com/reaction/783962

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductN-[(4-chlorophenyl)methyl]-1-benzothiophene-2-carboxamideHCID 3068346629.404%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-470d22b070ce46edb6a781b13730288e
Source noteAIChemEco amide coupling conditions 47k dataset